catalinagarcia

Genetic engineering of the immune system has shown great promise in the treatment of cancer, especially the use of chimeric antigen receptor (CAR)-T cells. Adoptive immunotherapy by using CD19-targeted CAR-T cells has had an acceptable potential for the treatment of chemotherapy-resistant and recurrent hematological malignancies, CAR molecular building is constructed by attaching an antigen recognition domain of antibodies to co-stimulatory and the zeta (ζ) signaling domains of T-cell receptor. Learn more: CAR Jurkat cell products